Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 6/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642163 | 0.84 | BLM (0.54) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL10643609 | 0.77 | CCNE1 (0.50) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11247946 | 0.75 | PNP (0.54) | BLMMEN1KMT2AYTHDC1P2RX7 | |
| SCHEMBL10638325 | 0.70 | LMNA (0.59) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| Phosphoric Acid SCHEMBL11324109 | 0.69 | PNP (0.51) | BLMP2RY1USP2PNPTSHR | |
| Ganciclovir SCHEMBL14491348 | 0.69 | BLM (0.60) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL20350686 | 0.68 | CDK1 (0.47) | CYP3A4HIF1AYTHDC1P2RX7P2RY1 | |
| SCHEMBL11258121 | 0.68 | CDK1 (0.51) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL14393416 | 0.68 | BLM (0.45) | BLMMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL13625720 | 0.68 | BLM (0.45) | BLMMEN1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072027-B1 | ANTIVIRAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-05-18 | — | — | EP | disclosed |