Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225104 | 0.79 | GAA (0.42) | HDAC1HDAC2POLBKDM4EGAA | |
| SCHEMBL22515644 | 0.78 | KDM4E (0.57) | HDAC1HDAC2KDM4EGAAKMT2A | |
| SCHEMBL10546411 | 0.73 | KMT2A (0.41) | HDAC1HDAC2POLBGAASMN1; SMN2 | |
| SCHEMBL8597022 | 0.72 | ATM (0.42) | POLBKMT2ARBP4 | |
| SCHEMBL10402214 | 0.72 | GAA (0.40) | HDAC1HDAC2POLBGAAL3MBTL1 | |
| Water SCHEMBL8600954 | 0.72 | ATM (0.42) | POLBKMT2ARBP4 | |
| SCHEMBL24044262 | 0.71 | GAA (0.42) | HDAC1HDAC2POLBGAAL3MBTL1 | |
| SCHEMBL10404631 | 0.71 | GAA (0.39) | HDAC1HDAC2POLBGAAL3MBTL1 | |
| SCHEMBL24454930 | 0.71 | POLB (0.38) | HDAC1HDAC2POLBKDM4EGAA | |
| SCHEMBL10265114 | 0.71 | ALDH1A1 (0.48) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253337-A2 | Tricyclic cepham compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |