Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22515644 | 0.76 | KDM4E (0.57) | HDAC1HDAC2GAAKDM4EALDH1A1 | |
| SCHEMBL16808292 | 0.74 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL24457797 | 0.74 | POLB (0.40) | POLBHDAC1HDAC2GAAL3MBTL1 | |
| SCHEMBL8597022 | 0.73 | ATM (0.42) | POLBLMNA | |
| SCHEMBL10205157 | 0.72 | KMT2A (0.49) | POLBHDAC1ALDH1A1 | |
| SCHEMBL9328091 | 0.71 | GAA (0.45) | POLBHDAC1HDAC2GAAL3MBTL1 | |
| SCHEMBL10644092 | 0.71 | HDAC1 (0.37) | POLBHDAC1HDAC2GAAL3MBTL1 | |
| SCHEMBL16804609 | 0.71 | DPP4 (0.39) | POLBHDAC1HDAC2GAAL3MBTL1 | |
| SCHEMBL9814590 | 0.71 | MEN1 (0.38) | POLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9332120 | 0.70 | POLB (0.39) | POLBHDAC1HDAC2GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022106611-A1 | NOVEL COMPOSITIONS OF BETA-LACTAM COMPOUNDS | XELLIA PHARMACEUTICALS APS (DK) | 2022-05-27 | — | — | WO | disclosed |