Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644246 | 1.00 | IDO1 (0.49) | IDO1KCNE1KCNQ1MAOAMAOB | |
| SCHEMBL7253517 | 1.00 | IDO1 (0.49) | IDO1KCNE1KCNQ1MAOAMAOB | |
| SCHEMBL21408674 | 0.85 | KCNE1 (0.51) | IDO1KCNE1KCNQ1MAOAMAOB | |
| SCHEMBL7777184 | 0.81 | KCNE1 (0.46) | IDO1KCNE1KCNQ1MAOAMAOB | |
| SCHEMBL28228605 | 0.79 | KCNE1 (0.42) | IDO1KCNE1KCNQ1MAOAMAOB | |
| SCHEMBL2818050 | 0.79 | KCNE1 (0.49) | KCNE1KCNQ1MAOAMAOBABCB1 | |
| SCHEMBL11187831 | 0.78 | IDO1 (0.40) | IDO1KCNE1KCNQ1L3MBTL1ABCC9 | |
| SCHEMBL11187833 | 0.78 | IDO1 (0.40) | IDO1KCNE1KCNQ1L3MBTL1ABCC9 | |
| SCHEMBL11187828 | 0.78 | IDO1 (0.40) | IDO1KCNE1KCNQ1L3MBTL1ABCC9 | |
| SCHEMBL9197778 | 0.77 | IDO1 (0.39) | IDO1KCNE1KCNQ1ABCB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4758677-A | Cyanobenzano [b] pyrans | BEECHAM GROUP P.L.C (GB) | 1988-07-19 | — | — | US | disclosed |
| US-4391815-A | VASODILATION, HYPOTENSIVE | BEECHAM GROUP LIMITED (GB) | 1983-07-05 | — | — | US | disclosed |