Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11187831 | 1.00 | IDO1 (0.40) | IDO1L3MBTL1CNR1KCNE1KCNQ1 | |
| SCHEMBL11187833 | 1.00 | IDO1 (0.40) | IDO1L3MBTL1CNR1KCNE1KCNQ1 | |
| SCHEMBL7253517 | 0.78 | IDO1 (0.49) | IDO1L3MBTL1KCNE1KCNQ1ABCC9 | |
| SCHEMBL10644246 | 0.78 | IDO1 (0.49) | IDO1L3MBTL1KCNE1KCNQ1ABCC9 | |
| SCHEMBL10644259 | 0.78 | IDO1 (0.49) | IDO1L3MBTL1KCNE1KCNQ1ABCC9 | |
| SCHEMBL10638859 | 0.73 | KCNE1 (0.52) | IDO1KCNE1KCNQ1ABCC9 | |
| SCHEMBL10638850 | 0.73 | KCNE1 (0.52) | IDO1KCNE1KCNQ1ABCC9 | |
| SCHEMBL10638845 | 0.73 | KCNE1 (0.52) | IDO1KCNE1KCNQ1ABCC9 | |
| SCHEMBL2006998 | 0.71 | L3MBTL1 (0.35) | IDO1L3MBTL1KCNE1KCNQ1ABCC9 | |
| SCHEMBL7328327 | 0.70 | ABCC9 (0.43) | IDO1KCNE1KCNQ1ABCC9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |