Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647317 | 0.93 | POLB (0.42) | KMT2AMEN1TP53POLBSMN1; SMN2 | |
| SCHEMBL10644308 | 0.91 | KMT2A (0.44) | KMT2AMEN1TP53POLBSMN1; SMN2 | |
| SCHEMBL10649177 | 0.91 | KDM4E (0.40) | KMT2AMEN1TP53POLBSMN1; SMN2 | |
| SCHEMBL10649425 | 0.89 | POLB (0.40) | KMT2AMEN1TP53POLBSMN1; SMN2 | |
| SCHEMBL10914095 | 0.86 | POLB (0.46) | KMT2AMEN1TP53POLBSMN1; SMN2 | |
| SCHEMBL10647313 | 0.85 | KDM4E (0.41) | TP53POLBSMN1; SMN2KDM4EHTT | |
| SCHEMBL10645304 | 0.85 | POLB (0.41) | KMT2AMEN1TP53POLBSMN1; SMN2 | |
| SCHEMBL10647011 | 0.85 | HTR1A (0.39) | KMT2AMEN1TP53BRD4KDM4E | |
| SCHEMBL10644672 | 0.84 | GAA (0.41) | KMT2AMEN1TP53POLBSMN1; SMN2 | |
| SCHEMBL9691692 | 0.84 | KMT2A (0.43) | KMT2AMEN1TP53POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288758-A2 | Dihydropyridinamides, process for their preparation and their use in medicines | BAYER AG (DE) | 1988-11-02 | — | — | EP | disclosed |