Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREB1 | P16220 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPRB | P23467 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656612 | 0.91 | LTA4H (0.41) | LTA4HTLR4ALDH1A1LMNAMAPT | |
| SCHEMBL9658095 | 0.90 | NR5A1 (0.42) | LTA4HTLR4ALDH1A1LMNAMAPT | |
| SCHEMBL9657016 | 0.89 | LTA4H (0.41) | CREB1LTA4HALDH1A1LMNAHTT | |
| SCHEMBL9656987 | 0.88 | NR5A1 (0.45) | LTA4HTLR4ALDH1A1LMNAHTT | |
| SCHEMBL9658493 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTMAPTATM | |
| SCHEMBL9628603 | 0.85 | HTT (0.48) | PTGS2ALDH1A1HTTMAPTCNR1 | |
| SCHEMBL9628487 | 0.83 | HTT (0.49) | PTGS2ALDH1A1HTTMAPTCNR1 | |
| SCHEMBL9629300 | 0.81 | KDM4E (0.38) | CREB1ALDH1A1HTTMAPTCNR1 | |
| SCHEMBL9629465 | 0.81 | MAPT (0.37) | CREB1ALDH1A1HTTMAPTCNR1 | |
| SCHEMBL9657099 | 0.81 | KDM4E (0.39) | CREB1LTA4HALDH1A1MAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |