Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500434 | 0.86 | RAB9A (0.76) | ALDH1A1RAB9AKMT2AHPGDMEN1 | |
| SCHEMBL10403483 | 0.82 | ALDH1A1 (0.69) | ALDH1A1RAB9AKMT2AHPGDMEN1 | |
| SCHEMBL10403480 | 0.82 | ALDH1A1 (0.69) | ALDH1A1RAB9AKMT2AHPGDMEN1 | |
| SCHEMBL10402073 | 0.81 | ALDH1A1 (0.68) | ALDH1A1RAB9AKMT2AHPGDMEN1 | |
| SCHEMBL10402071 | 0.81 | ALDH1A1 (0.68) | ALDH1A1RAB9AKMT2AHPGDMEN1 | |
| SCHEMBL10644975 | 0.81 | HTT (0.54) | ALDH1A1RAB9AKMT2AHPGDMEN1 | |
| SCHEMBL10760459 | 0.81 | ALDH1A1 (0.72) | ALDH1A1RAB9AKMT2AHPGDMEN1 | |
| SCHEMBL14825049 | 0.79 | RAB9A (0.73) | ALDH1A1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL12487254 | 0.79 | TSHR (1.00) | ALDH1A1RAB9AKMT2AHPGDMEN1 | |
| SCHEMBL11275157 | 0.79 | ALDH1A1 (0.72) | ALDH1A1RAB9AKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009149054-A1 | SMALL MOLECULE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DENGUE VIRUS INFECTION | SIGA TECHNOLOGIES, INC. (US) | 2009-12-10 | — | — | WO | disclosed |
| US-4719036-A | PAINTS; METAL WORKING | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0006347-B1 | COMPOSITIONS AND METHOD FOR REGULATING SOYBEAN PLANT GROWTH UTILIZING SUBSTITUTED BENZAZOLYLTHIOALKANOIC ACIDS | MONSANTO COMPANY (US) | 1984-01-25 | — | — | EP | disclosed |
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |