Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265311 | 0.80 | KDM4E (0.30) | KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL6262974 | 0.71 | LATS1 (0.30) | LATS1 | |
| Iodide SCHEMBL11855940 | 0.70 | GAA (0.32) | TSHR | |
| SCHEMBL11855672 | 0.68 | KDM4E (0.32) | LATS1KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL10744254 | 0.68 | GAA (0.35) | KDM4ETSHRRXRARXRGCYP1A2 | |
| SCHEMBL6258367 | 0.66 | KDM4E (0.36) | KDM4EUSP2ALDH1A1TSHRSLC6A3 | |
| SCHEMBL9974040 | 0.61 | HCAR2 (0.38) | — | |
| SCHEMBL4495310 | 0.61 | CYP1A2 (0.44) | KDM4EUSP2ALDH1A1TSHRRARA | |
| Iodide SCHEMBL11855948 | 0.59 | — | — | |
| SCHEMBL11800786 | 0.58 | CHRNB2 (0.40) | ALDH1A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192931-B1 | PROCESS FOR THE PREPARATION OF ISOXAZOLES | FIRMENICH SA (CH) | 1988-09-07 | — | — | EP | claimed |
| EP-0192931-A1 | Process for the preparation of isoxazoles | FIRMENICH SA (CH) | 1986-09-03 | — | — | EP | claimed |
| EP-0192931-B1 | PROCESS FOR THE PREPARATION OF ISOXAZOLES | FIRMENICH SA (CH) | 1988-09-07 | — | — | EP | disclosed |
| US-4670109-A | ANODIC OXIDATION OF ALPHA-BETA UNSATURATED OXIMES | FIRMENICH SA (CH) | 1987-06-02 | — | — | US | disclosed |
| EP-0192931-A1 | Process for the preparation of isoxazoles | FIRMENICH SA (CH) | 1986-09-03 | — | — | EP | disclosed |
| US-3968161-A | MULTISTAGE | FIRMENICH S.A. (CH) | 1976-07-06 | — | — | US | disclosed |
| US-3931323-A | Process for the preparation of alkenoyl-substituted cyclohexenes | FIRMENICH SA (CH) | 1976-01-06 | — | — | US | disclosed |