Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265311 | 0.63 | KDM4E (0.30) | KDM4EUSP2ALDH1A1TSHR | |
| SCHEMBL22679771 | 0.62 | BRD4 (0.46) | KDM4EALDH1A1HSD17B10HTTPOLB | |
| SCHEMBL11619376 | 0.60 | PTGS2 (0.49) | KDM4EALDH1A1TSHRHSD17B10HTT | |
| SCHEMBL11786351 | 0.60 | CYP1A2 (0.51) | KDM4EUSP2ALDH1A1TSHRCSF1R | |
| SCHEMBL18255923 | 0.59 | CHRNB2 (0.45) | KDM4EALDH1A1TSHRSLC6A3MAPT | |
| SCHEMBL13514282 | 0.58 | CYP1A2 (0.54) | KDM4EUSP2ALDH1A1TSHRMAPT | |
| SCHEMBL1396725 | 0.58 | — | — | |
| SCHEMBL10519198 | 0.57 | NPC1 (0.56) | KDM4EALDH1A1HSD17B10HTTPOLB | |
| SCHEMBL4145079 | 0.57 | CYP1A2 (0.45) | KDM4EUSP2ALDH1A1TSHRMAPT | |
| SCHEMBL2270503 | 0.57 | NPC1 (0.59) | ALDH1A1TSHRCSF1RPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085016-B1 | HETEROCYCLE-BEARING THIO PHENOL COMPOUNDS, INTERMEDIATES FOR THE PREPARATION OF THE SAME AND PROCESSES FOR THE PREPARATION OF BOTH | NIPPON SODA CO (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-6359143-B1 | CHEMICAL INTERMEDIATE; HERBICIDES | NIPPON SODA CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1085016-A1 | HETEROCYCLE-BEARING THIO PHENOL COMPOUNDS, INTERMEDIATES FOR THE PREPARATION OF THE SAME AND PROCESSES FOR THE PREPARATION OF BOTH | NIPPON SODA CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |