Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649926 | 0.80 | IDH1 (0.58) | IDH1MEN1KMT2ATSHR | |
| SCHEMBL1935834 | 0.80 | MAPT (0.48) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6620223 | 0.79 | MAPT (0.46) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL13141321 | 0.79 | MAPT (0.54) | SMN1; SMN2CYP4F2CYP4A11MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4677525 | 0.79 | IDH1 (0.57) | IDH1MEN1KMT2ATSHR | |
| SCHEMBL28150896 | 0.78 | IDH1 (0.53) | IDH1 | |
| SCHEMBL27262070 | 0.78 | TNKS (0.50) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL1934170 | 0.78 | MAPT (0.54) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL23188993 | 0.77 | PLA2G2A (0.56) | SMN1; SMN2IDH1MEN1KMT2AMAPT | |
| SCHEMBL1936827 | 0.77 | MAPT (0.47) | SMN1; SMN2MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117563-B1 | PRODUCTION OF ALKYL-5-SUBSTITUTED-3-FUROATE COMPOUNDS | BIO-UCLAF CORPORATION (US) | 1988-02-03 | — | — | EP | disclosed |
| US-4477679-A | Production of alkyl-5-substituted-3-furoate compounds | CPC INTERNATIONAL INC. (US) | 1984-10-16 | — | — | US | disclosed |
| EP-0117563-A2 | Production of alkyl-5-substituted-3-furoate compounds | BIO-UCLAF CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |