SCHEMBL28150896

SCHEMBL28150896

CNC(=O)c1coc(Cc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.53
BRD4 O60885 9/20 0.50
BRD2 P25440 1/20 0.43
BRD3 Q15059 1/20 0.43
BRDT Q58F21 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SLC7A5 Q01650 1/20 0.43
KLK7 P49862 1/20 0.43
PLK1 P53350 1/20 0.41
LMNA P02545 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10649926 0.83 IDH1 (0.58) IDH1L3MBTL1LMNA
Hydrochloric Acid SCHEMBL4677525 0.82 IDH1 (0.57) IDH1L3MBTL1LMNA
SCHEMBL23188993 0.81 PLA2G2A (0.56) IDH1BRD4L3MBTL1LMNA
SCHEMBL4677523 0.81 IDH1 (0.55) IDH1L3MBTL1KLK7LMNA
SCHEMBL13368525 0.78 PLK1 (0.47) BRD4L3MBTL1PLK1LMNA
SCHEMBL10645501 0.78 SMN1; SMN2 (0.50) IDH1
SCHEMBL4488736 0.77 L3MBTL1 (0.44) L3MBTL1SLC7A5PLK1LMNA
Methylamine SCHEMBL4481996 0.76 L3MBTL1 (0.43) L3MBTL1SLC7A5PLK1LMNA
SCHEMBL4674730 0.75 IDH1 (0.49) IDH1KLK7LMNA
SCHEMBL4674726 0.75 IDH1 (0.49) IDH1KLK7LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106659161-B Amide compound and its harmful arthropod prevent and kill off purposes 住友化学株式会社 2019-08-02 CN disclosed
CN-106659161-A Amide compound and use of same for noxious arthropod control 住友化学株式会社 2017-05-10 CN disclosed