Pyrimidine

Pyrimidine

SCHEMBL10646

c1cncnc1.c1cncnc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP2A6 P11509 2/20 0.40
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
HSP90AA1 P07900 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL1846 1.00
Pyrimidine SCHEMBL19437633 1.00 TSHR (0.50) TSHRNAPRTTDP1CYP2A6ALDH1A1
Pyrimidine SCHEMBL606542 0.95
Pyrimidine SCHEMBL3987505 0.95
Pyrimidine SCHEMBL1054141 0.95
Pyrimidine SCHEMBL383109 0.95
Pyrimidine SCHEMBL9120472 0.95
Pyrimidine SCHEMBL21315895 0.95 TSHR (0.46) TSHRNAPRTTDP1CYP2A6ALDH1A1
Pyrimidine SCHEMBL22346941 0.95
Pyrimidine SCHEMBL9545353 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190003966-A1 Ultraviolet and High-Performance Liquid Chromatography Methods for the Evaluation of Sunscreen Efficacy SENA RESEARCH, INCORPORATED (US) 2019-01-03 US claimed
EP-2780303-A1 SEPARATION TECHNIQUE, PHOTO-OXIDATION OF ORGANIC SUBSTRATES, AND PHOTO CATALYSTS The University Of Nottingham (GB) 2014-09-24 EP claimed
US-20130183765-A1 Ultraviolet and High-Performance Liquid Chromatography Methods for the Evaluation of Sunscreen Efficacy Sena Research Incorporated (US) 2013-07-18 US claimed
WO-2013072678-A1 SEPARATION TECHNIQUE, PHOTO-OXIDATION OF ORGANIC SUBSTRATES, AND PHOTO CATALYSTS THE UNIVERSITY OF NOTTINGHAM (GB) 2013-05-23 WO claimed
WO-2013058767-A1 MATERIALS AND METHODS TO DETECT PYRIMIDINE-PYRIMIDINE DIMER FORMATION EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-04-25 WO claimed
WO-2012037158-A2 ULTRAVIOLET AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHODS FOR THE EVALUATION OF SUNSCREEN EFFICACY SENA RESEARCH, INCORPORATED (US) 2012-03-22 WO claimed
US-20090246853-A1 DIRECTED EVOLUTION METHOD MEDICAL RESEARCH COUNCIL (GB) 2009-10-01 US claimed
EP-1806406-A2 Directed evolution method Medical Research Council (GB) 2007-07-11 EP claimed
US-20050031638-A1 Vaccine SMITHKLINE BEECHAM BIOLOGICALS S.A. 2005-02-10 US claimed
US-20040005594-A1 Directed evolution method MEDICAL RESEARCH COUNCIL 2004-01-08 US claimed
EP-1317539-A2 DIRECTED EVOLUTION METHOD MEDICAL RESEARCH COUNCIL (GB) 2003-06-11 EP claimed
WO-2002022869-A2 DIRECTED EVOLUTION METHOD MEDICAL RESEARCH COUNCIL (GB) 2002-03-21 WO claimed
EP-1040123-A2 HUMAN PAPILLOMAVIRUS VACCINE SMITHKLINE BEECHAM BIOLOGICALS s.a. (BE) 2000-10-04 EP claimed
WO-2000054803-A2 IMMUNOSTIMULATORY NUCLEIC ACIDS AND ANTIGENS PANACEA PHARMACEUTICALS, LLC (US) 2000-09-21 WO claimed
WO-1999033868-A2 HUMAN PAPILLOMAVIRUS VACCINE SMITHKLINE BEECHAM BIOLOGICALS S.A. (BE) 1999-07-08 WO claimed
US-20250367419-A1 DRUG DELIVERY SYSTEM COMPRISING AN AGENT EFFECTIVE IN THE TREATMENT OR PREVENTION OF AN ESOPHAGEAL DISEASE FOR THE APPLICATION TO ESOPHAGEAL MUCOUS MEMBRANES ESOCAP AG (CH) 2025-12-04 US disclosed
EP-4536195-A1 DRUG DELIVERY SYSTEM COMPRISING AN AGENT EFFECTIVE IN THE TREATMENT OR PREVENTION OF AN ESOPHAGEAL DISEASE FOR THE APPLICATION TO ESOPHAGEAL MUCOUS MEMBRANES EsoCap AG (CH) 2025-04-16 EP disclosed
EP-0167238-A1 Displacement polynucleotide assay method and polynucleotide complex reagent therefor ALLIED CORPORATION (US) 1986-01-08 EP disclosed
EP-0164876-A1 Displacement polynucleotide assay employing recombination protein and diagnostic kit ALLIED CORPORATION (US) 1985-12-18 EP disclosed
US-4184271-A Molecular model BARNETT JAMES W JR 1980-01-22 US disclosed