⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL10646 | 1.00 | TSHR (0.50) | — | |
| Pyrimidine SCHEMBL19437633 | 1.00 | TSHR (0.50) | — | |
| Pyrimidine SCHEMBL606542 | 0.95 | — | — | |
| Pyrimidine SCHEMBL3987505 | 0.95 | — | — | |
| Pyrimidine SCHEMBL1054141 | 0.95 | — | — | |
| Pyrimidine SCHEMBL383109 | 0.95 | — | — | |
| Pyrimidine SCHEMBL9120472 | 0.95 | — | — | |
| Pyrimidine SCHEMBL21315895 | 0.95 | TSHR (0.46) | — | |
| Pyrimidine SCHEMBL22346941 | 0.95 | — | — | |
| Pyrimidine SCHEMBL9545353 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 652010 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6433115-B1 | — | — | None | — | — | US | claimed |
| EP-1855694-B1 | ANTISENSE COMPOSITION FOR TREATING MUSCLE ATROPHY | SAREPTA THERAPEUTICS INC (US) | 2020-12-02 | — | — | EP | claimed |
| US-RE46856-E1 | Substituted 2,3-dihydroimidazo[1,2-c]quinazoline derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-05-22 | — | — | US | claimed |
| US-9974839-B2 | Self-assembled toroidal-spiral particles and manufacture and uses thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-05-22 | — | — | US | claimed |
| US-9975895-B2 | Substituted pyrimidinium compounds and derivatives for combating animal pests | BASF SE (DE) | 2018-05-22 | — | — | US | claimed |
| US-9974795-B2 | Anticancer agent composition | CARNA BIOSCIENCES, INC. (JP) | 2018-05-22 | — | — | US | claimed |
| US-9978956-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-05-22 | — | — | US | claimed |
| US-20180138416-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-05-17 | — | — | US | claimed |
| US-20180134688-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-05-17 | — | — | US | claimed |
| US-20180133219-A1 | BIHETEROARYL COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2018-05-17 | — | — | US | claimed |
| US-3954759-A | GERMICIDES, ANTINEOPLASTIC, CANCER CHEMOTHERAPY | PCR, INC. (US) | 1976-05-04 | — | — | US | claimed |
| US-3953345-A | Method for the production of activated carbon spheres containing nitrogen | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1976-04-27 | — | — | US | claimed |
| US-3951955-A | ANTIMICROBIAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | claimed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | claimed |
| US-3947441-A | Substituted 2-amino-4-(hydroxyamino)-pyrimidines | CIBA-GEIGY CORPORATION (US) | 1976-03-30 | — | — | US | claimed |
| US-3942537-A | Novel flavoring compositions and processes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-03-09 | — | — | US | claimed |
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | claimed |
| US-3936332-A | DIAZINE, PEROXYSULFATE, HALOGEN COMPOUND | TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) | 1976-02-03 | — | — | US | claimed |
| US-3936452-A | Process of producing pyrimidyl thiocarbonates | NITTO BOSEKI CO., LTD. (JA) | 1976-02-03 | — | — | US | claimed |
| US-3932366-A | FROM AMINOCARBOXYLIC ACIDS AND TRIAMINES, FIBER REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | claimed |