⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL1054141 | 1.00 | — | — | |
| Pyrimidine SCHEMBL28123331 | 0.95 | — | — | |
| Pyrimidine SCHEMBL28148519 | 0.95 | — | — | |
| Pyrimidine SCHEMBL1846 | 0.95 | — | — | |
| Pyrimidine SCHEMBL10646 | 0.95 | TSHR (0.50) | — | |
| Pyrimidine SCHEMBL19437633 | 0.95 | TSHR (0.50) | — | |
| Pyrimidine SCHEMBL9545353 | 0.90 | — | — | |
| Pyrimidine SCHEMBL1662110 | 0.90 | — | — | |
| Pyrimidine SCHEMBL22346941 | 0.90 | — | — | |
| Pyrimidine SCHEMBL21315895 | 0.90 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114261149-B | Polyimide arc-proof clothing fabric and arc-proof clothing | 江苏先诺新材料科技有限公司 | 2024-08-13 | — | — | CN | claimed |
| WO-2024130030-A1 | METHOD FOR TREATING NEUROLOGICAL DISEASES THROUGH GLIAL PRUNING REGULATION | FRED HUTCHINSON CANCER CENTER (US) | 2024-06-20 | — | — | WO | claimed |
| CN-109776427-B | Pyrimidine diamine compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-08-23 | — | — | CN | claimed |
| US-20220249475-A1 | COMPOUNDS AND METHOD FOR TREATING CYTOKINE RELEASE SYNDROME | RIGEL PHARMACEUTICALS, INC. (US) | 2022-08-11 | — | — | US | claimed |
| EP-4009974-A1 | COMPOUNDS AND METHOD FOR TREATING CYTOKINE RELEASE SYNDROME | Rigel Pharmaceuticals, Inc. (US) | 2022-06-15 | — | — | EP | claimed |
| CN-114261149-A | Polyimide arc-proof garment fabric and arc-proof garment | 江苏先诺新材料科技有限公司 | 2022-04-01 | — | — | CN | claimed |
| WO-2021026451-A1 | COMPOUNDS AND METHOD FOR TREATING CYTOKINE RELEASE SYNDROME | RIGEL PHARMACEUTICALS, INC. (US) | 2021-02-11 | — | — | WO | claimed |
| US-20200216431-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2020-07-09 | — | — | US | claimed |
| CN-122103234-A | Pyrimidine diamine compound and application thereof | — | 2026-05-29 | — | — | CN | disclosed |
| CN-122103234-A | Pyrimidine diamine compound and application thereof | — | 2026-05-29 | — | — | CN | disclosed |
| CN-116789643-B | 2-Aminopyrimidine compound and preparation method and application thereof | 海南医学院 | 2025-05-06 | — | — | CN | disclosed |
| CN-114261149-B | Polyimide arc-proof clothing fabric and arc-proof clothing | 江苏先诺新材料科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118317620-A | Light emitting device and display apparatus including the same | 三星电子株式会社 | 2024-07-09 | — | — | CN | disclosed |
| CN-118234377-A | Method for improving efficacy of herbicides | 巴斯夫欧洲公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20050049220-A1 | Dosing regimen for Flaviviridae therapy | PHARMASSET, INC. | 2005-03-03 | — | — | US | disclosed |
| WO-2005018330-A1 | DOSING REGIMEN FOR FLAVIVIRIDAE THERAPY | PHARMASSET, INC. (US) | 2005-03-03 | — | — | WO | disclosed |
| WO-2005009418-A2 | PURINE NUCLEOSIDE ANALOGUES FOR TREATING DISEASES CAUSED BY FLAVIVIRIDAE INCLUDING HEPATITIS C | IDENIX (CAYMAN) LIMITED (KY) | 2005-02-03 | — | — | WO | disclosed |
| US-20030162664-A1 | Surfactant coated products and methods for their use in promoting plant growth and soil remediation | JAR-MAR, INC. | 2003-08-28 | — | — | US | disclosed |
| US-6565860-B1 | Agricultural mixtures containing fertilizer | JAY-MAR, INC. | 2003-05-20 | — | — | US | disclosed |
| US-6110866-A | MIXING TOGETHER A POLYGLYCOL ETHER AND AN OXIDIZER SELECTED FROM NAPHTHALENEACETIC ACID, CHROMIC ACID, PERMAGANATE, AND HYPOCHLORITE TOGETHER WITH SOIL ADDITIVE CARRIERS SUCH AS A FERTILIZER, ANTICAKING AGENT AND PESTICIDE | JAY-MAR, INC. (US) | 2000-08-29 | — | — | US | disclosed |