Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534240 | 0.95 | HPGD (0.47) | HPGDMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL10532195 | 0.91 | MAPT (0.48) | HPGDMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL10532390 | 0.90 | MAPT (0.46) | HPGDMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL10645372 | 0.89 | ALDH1A1 (0.45) | HPGDMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL10534168 | 0.89 | PDE4A (0.49) | HPGDALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL10532541 | 0.86 | MAPT (0.51) | HPGDMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL10534136 | 0.86 | ALDH1A1 (0.47) | HPGDMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL10531461 | 0.85 | AURKA (0.42) | KMT2AMEN1AURKAAURKBPDE4A | |
| SCHEMBL10532566 | 0.83 | PDE4A (0.51) | HPGDMAPTALDH1A1RAB9AKDM4E | |
| SCHEMBL10530386 | 0.83 | SLC2A1 (0.43) | HPGDMAPTALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263352-A1 | Imidazo-benzoxazinones, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-04-13 | — | — | EP | disclosed |