Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10500072 | 1.00 | TSHR (0.44) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL5654625 | 0.89 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1636584 | 0.89 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1636583 | 0.89 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL5586259 | 0.82 | THRB (0.47) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL472711 | 0.82 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL7673065 | 0.82 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL6817186 | 0.82 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL453100 | 0.79 | TSHR (0.47) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL37916 | 0.79 | TSHR (0.47) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725629-A | Process of making an interpenetrating superabsorbent polyurethane foam | KIMBERLY-CLARK CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-4379838-A | Photosensitive photographic recording material comprising a dyed layer | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1983-04-12 | — | — | US | disclosed |
| US-4353972-A | ACRYLIC ESTER POLYMER CONTAINING QUATERNARY AMMONIUM OR PHOSPHONIUM GROUPS | AGFA-GEVAERT AG (DE) | 1982-10-12 | — | — | US | disclosed |
| US-4260812-A | Process for the preparation of halogen butenyl acrylates | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |