SCHEMBL5654625

SCHEMBL5654625

C=C(C)C(=O)OC/C=C\COC(=O)C(=C)C

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
THRB P10828 1/20 0.48
ALDH1A1 P00352 5/20 0.46
TDP1 Q9NUW8 3/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
GLO1 Q04760 1/20 0.32
HSD17B10 Q99714 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1636583 1.00 TSHR (0.52) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL1636584 1.00 TSHR (0.52) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL6817186 0.91 TSHR (0.45) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL5586259 0.91 THRB (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL472711 0.91 TSHR (0.45) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL10647271 0.89 TSHR (0.44) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL10500072 0.89 TSHR (0.44) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL10606524 0.89 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL37916 0.89 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL453100 0.89 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060178493-A1 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-08-10 US claimed
US-7022789-B2 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-04-04 US claimed
US-20050176906-A1 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2005-08-11 US claimed
US-20020169263-A1 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-11-14 US claimed
US-20240018298-A1 OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS ExxonMobil Product Solutions Company 2024-01-18 US disclosed
US-11535696-B2 Crosslinkable composition and crosslinked product ZEON CORPORATION (JP) 2022-12-27 US disclosed
US-11267956-B2 Rubber composition and rubber crosslinked product ZEON CORPORATION (JP) 2022-03-08 US disclosed
EP-3533829-B1 RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2021-11-24 EP disclosed
CN-109890895-B Crosslinkable composition and crosslinked product 日本瑞翁株式会社 2021-08-27 CN disclosed
CN-109844008-B Rubber composition and crosslinked rubber 日本瑞翁株式会社 2021-08-24 CN disclosed
US-20200055975-A1 CROSSLINKABLE COMPOSITION AND CROSSLINKED PRODUCT ZEON CORPORATION (JP) 2020-02-20 US disclosed
EP-3533829-A1 RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT Zeon Corporation (JP) 2019-09-04 EP disclosed
US-20190256692-A1 RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORPORATION (JP) 2019-08-22 US disclosed
US-20120142865-A1 NANOSTRUCTURED POLYMER MEMBRANES FOR SELECTIVE ALCOHOL TRANSPORT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-06-07 US disclosed
US-20060178493-A1 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-08-10 US disclosed
US-7022789-B2 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2006-04-04 US disclosed
US-20050176906-A1 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2005-08-11 US disclosed
US-6867274-B2 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2005-03-15 US disclosed
US-20020169263-A1 Telechelic alkadiene polymers with crosslinkable end groups and methods for making the same CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-11-14 US disclosed
US-6465590-B1 FROM REACTION OF A FUNCTIONALIZED CHAIN TRANSFER AGENT HAVING CROSSLINKABLE ENDS WITH A CYCLOALKENE CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142865-A1 NANOSTRUCTURED POLYMER MEMBRANES FOR SELECTIVE ALCOHOL TRANSPORT SLC6A11, PCNA, ABCB11 TSHR 2986/4885THRB 1222/4885ALDH1A1 2533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.