Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Anisaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A known ✓ | P04350 | 1/20 | 0.45 |
| ▸ | TUBB known ✓ | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C known ✓ | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B known ✓ | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A known ✓ | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B known ✓ | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 known ✓ | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A known ✓ | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 known ✓ | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E known ✓ | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A known ✓ | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C known ✓ | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 known ✓ | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B known ✓ | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 known ✓ | Q9H4B7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisaldehyde SCHEMBL8666282 | 0.98 | ALDH1A1 (0.66) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL28223592 | 0.95 | ALDH1A1 (0.70) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL9090048 | 0.93 | ALDH1A1 (0.79) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL888255 | 0.93 | ALDH1A1 (0.79) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL15602807 | 0.91 | ALDH1A1 (0.76) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL2357398 | 0.86 | ALDH1A1 (0.54) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL6910607 | 0.86 | ALDH1A1 (0.68) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL28156946 | 0.85 | ALDH1A1 (0.79) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL2239445 | 0.82 | ALDH1A1 (0.91) | ALDH1A1CYP2A6THRBATMF3 | |
| Anisaldehyde SCHEMBL1100 | 0.82 | ALDH1A1 (1.00) | ALDH1A1CYP2A6THRBATMF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680062-B2 | System for delivering therapeutic agents into living cells and cells nuclei | Deliversir Ltd. (IL) | 2014-03-25 | — | — | US | disclosed |
| US-8647875-B2 | Enzymes involved in triterpene synthesis | PLANT BIOSCIENCES LIMITED (GB) | 2014-02-11 | — | — | US | disclosed |
| US-8614369-B2 | Enzymes involved in triterpene synthesis | PLANT BIOSCIENCE LIMITED (GB) | 2013-12-24 | — | — | US | disclosed |
| US-20130247245-A1 | ENZYMES INVOLVED IN TRITERPENE SYNTHESIS | PLANT BIOSCIENCE LIMITED (GB) | 2013-09-19 | — | — | US | disclosed |
| US-8470995-B2 | Enzymes involved in triterpene synthesis | PLANT BIOSCIENCE LIMITED (GB) | 2013-06-25 | — | — | US | disclosed |
| US-8175817-B2 | Reciprocal symmetry plots as a new representation of countercurrent chromatograms | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-05-08 | — | — | US | disclosed |
| US-20110023182-A1 | ENZYMES INVOLVED IN TRITERPENE SYNTHESIS | PLANT BIOSCIENCE LIMITED (GB) | 2011-01-27 | — | — | US | disclosed |
| EP-2167654-A2 | ENZYMES INVOLVED IN TRITERPENE SYNTHESIS | Plant Bioscience Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009041932-A2 | ENZYMES INVOLVED IN TRITERPENE SYNTHESIS | PLANT BIOSCIENCE LIMITED (GB) | 2009-04-02 | — | — | WO | disclosed |
| US-20080250531-A1 | ENZYMES INVOLVED IN TRITERPENE SYNTHESIS | OSBOURN ANNE | 2008-10-09 | — | — | US | disclosed |
| EP-0264173-B1 | BRYOSTATINS | ARIZONA BOARD OF REGENTS (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0428367-A1 | Isolation and structural elucidation of the cytostatic linear depsipetide dolastatin 14 | ARIZONA BOARD OF REGENTS (US) | 1991-05-22 | — | — | EP | disclosed |
| US-4986988-A | ANTITUMOR AGENTS | ARIZONA BOARD OF REGENTS (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0398558-A1 | Isolation and structual elucidation of the cytostatic linear depsipeptide dolastatin 15 | ARIZONA BOARD OF REGENTS (US) | 1990-11-22 | — | — | EP | disclosed |
| US-4879278-A | ANTINEOPLASTIC | ARIZONA BOARD OF REGENTS (US) | 1989-11-07 | — | — | US | disclosed |
| US-4873245-A | ANTICARCINOGENIC AGENTS; LEUKEMIA | ARIZONA BOARD OF REGENTS (US) | 1989-10-10 | — | — | US | disclosed |
| US-4833257-A | BRYOSTATIN, ANTITUMOR AGENTS | ARIZONA BOARD OF REGENTS (US) | 1989-05-23 | — | — | US | disclosed |
| EP-0264173-A2 | Bryostatins | ARIZONA BOARD OF REGENTS (US) | 1988-04-20 | — | — | EP | disclosed |
| EP-0178048-A1 | Bryostatins | ARIZONA BOARD OF REGENTS, ARIZONA STATE UNIVERSITY (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4146615-A | GLYCOSIDE OF ECHINOCYSTIC ACID, ANALGESIC, ANTIINFLAMMATORY, ANTIULCER | LABORATOIRES SARGET (FR) | 1979-03-27 | — | — | US | disclosed |