Ethyl Acetate

Ethyl Acetate

SCHEMBL10647601

CCOC(C)=O.[Cl-].[Cl-].[Cl-].[Fe+3]

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Ethyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 2/20 0.44
CHRM3 known ✓ P20309 2/20 0.44
CHRM2 known ✓ P08172 1/20 0.40
ALDH1A1 P00352 5/20 0.88
LMNA P02545 1/20 0.88
HSD17B10 Q99714 1/20 0.88
TSHR P16473 1/20 0.52
GAA P10253 2/20 0.48
ALOX15 P16050 1/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
SOAT1 P35610 1/20 0.48
CHRM5 P08912 2/20 0.44
TRPA1 O75762 1/20 0.43
GLO1 Q04760 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL28114359 0.94
Ethyl Acetate SCHEMBL11819132 0.94 ALDH1A1 (0.88) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL28136114 0.94
Ethyl Acetate SCHEMBL8580955 0.94
Ethyl Acetate SCHEMBL261878 0.94
Ethyl Acetate SCHEMBL28457765 0.94 ALDH1A1 (1.00) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL1331990 0.94
Ethyl Acetate SCHEMBL28615209 0.94 ALDH1A1 (1.00) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL8506185 0.94 ALDH1A1 (1.00) ALDH1A1LMNAHSD17B10TSHRGAA
Ethyl Acetate SCHEMBL1331901 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0293078-A1 Pharmaceutically active amines THE UPJOHN COMPANY (US) 1988-11-30 EP disclosed