Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | HPD | P32754 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327555 | 0.80 | CYP3A4 (0.47) | MAOBIDO1MAOA | |
| SCHEMBL6433409 | 0.75 | HTT (0.44) | MAOBMAOA | |
| SCHEMBL4404036 | 0.71 | MAOB (1.00) | MAOBIDO1AGXTMAOAPARP15 | |
| SCHEMBL12256032 | 0.70 | MAOB (0.66) | MAOBIDO1AGXTMAOAPARP15 | |
| SCHEMBL1767187 | 0.69 | IDO1 (0.69) | MAOBIDO1AGXTMAOAPARP15 | |
| SCHEMBL13469158 | 0.69 | MAOB (0.82) | MAOBIDO1AGXTMAOAPARP15 | |
| SCHEMBL16142823 | 0.69 | CARM1 (0.59) | MAOBIDO1AGXTMAOA | |
| SCHEMBL8491985 | 0.68 | MAOB (0.62) | MAOBIDO1AGXTMAOAPARP15 | |
| SCHEMBL22305499 | 0.68 | CARM1 (0.58) | MAOBIDO1AGXTMAOA | |
| SCHEMBL22305500 | 0.68 | MAOB (0.49) | MAOBIDO1AGXTMAOAPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296802-A1 | Aminocyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1988-12-28 | — | — | EP | disclosed |