Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327555 | 0.94 | CYP3A4 (0.47) | HTTHTR1ACYP3A4ALOX15MAOB | |
| SCHEMBL6440010 | 0.78 | HRH3 (0.35) | HTTHTR1AHTR7HTR6CYP3A4 | |
| SCHEMBL10041855 | 0.75 | MAOB (0.50) | MAOBBCHEHRH3LMNACYP1A2 | |
| SCHEMBL10647672 | 0.75 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL3278335 | 0.74 | TSHR (0.48) | HTR1AMAOBBCHEHRH3TSHR | |
| SCHEMBL17072360 | 0.74 | GSTP1 (0.49) | MAOBBCHEHRH3LMNACYP1A2 | |
| Phenol SCHEMBL9511612 | 0.73 | CA12 (0.44) | CYP3A4ALOX15TSHRTDP1MAPT | |
| SCHEMBL1061320 | 0.72 | TSHR (0.46) | MAOBBCHEHRH3TSHRLMNA | |
| SCHEMBL14305067 | 0.71 | HTT (0.49) | HTTHTR1AHTR6MAOBTSHR | |
| SCHEMBL5356568 | 0.71 | HTT (0.53) | HTTMAOBTDP1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315735-B | Dihydrobenzimidazolone | C4医药公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023226920-A1 | AMINOHETEROARYL KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO.,LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| CN-104922128-B | Inhibitors of influenza virus replication | 沃泰克斯药物股份有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-110540538-A | Inhibitors of influenza virus replication | VERTEX PHARMA | 2019-12-06 | — | — | CN | disclosed |
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1134207-A1 | Process for preparing resorcinol derivatives | Pfizer Products Inc. (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |
| EP-0043041-B1 | PROCESS FOR PREPARING HIGH-VISCOSITY POLYCHLOROPRENE AND USE THEREOF AS RAW MATERIAL IN ADHESIVES | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| US-4405742-A | Process for the production of high molecular weight polychloroprene and its use as a starting material for adhesives | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |
| EP-0043041-A1 | Process for preparing high-viscosity polychloroprene and use thereof as raw material in adhesives | BAYER AG (DE) | 1982-01-06 | — | — | EP | disclosed |