SCHEMBL10648019

SCHEMBL10648019

C#CC(CCC)(CCCc1cccc(Oc2ccccc2)c1)c1ccc(OCC)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.44
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CETP P11597 1/20 0.38
FDFT1 P37268 4/20 0.37
FFAR1 O14842 3/20 0.37
FFAR4 Q5NUL3 1/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10648184 0.96 LTA4H (0.44) LTA4HTSHRHSD17B10CETPFDFT1
SCHEMBL10649141 0.93 LTA4H (0.45) LTA4HTSHRHSD17B10CETPFDFT1
SCHEMBL10649132 0.89 BCHE (0.39) LTA4HTSHRHSD17B10CETPFDFT1
SCHEMBL10647349 0.88 ALDH1A1 (0.40) TSHRHSD17B10CETPFDFT1PPARG
SCHEMBL10648044 0.88 FDFT1 (0.44) LTA4HTSHRHSD17B10CETPFDFT1
SCHEMBL10649279 0.88 LTA4H (0.48) LTA4HTSHRHSD17B10CETPFDFT1
SCHEMBL10649112 0.87 TSHR (0.38) TSHRHSD17B10CETPFDFT1PPARG
SCHEMBL10647483 0.87 LTA4H (0.44) LTA4HTSHRHSD17B10CETPFDFT1
SCHEMBL10648950 0.87 FDFT1 (0.40) LTA4HCETPFDFT1PPARGPPARA
SCHEMBL10649076 0.86 FFAR1 (0.35) TSHRHSD17B10CETPFDFT1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0193189-B1 NOVEL COMPOUND, ITS PRODUCTION AND INSECTICIDAL AND ACARICIDAL COMPOSITION CONTAINING IT AS AN ACTIVE INGREDIENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-28 EP disclosed
US-4772633-A 6-pyridyl- and 6-phenyl-3-phenyl-1-hexenes and -1-hexynes, composition containing them, and insecticidal and acaricidal method of using them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-09-20 US disclosed