Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 20/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | PTGIS | Q16647 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031173 | 0.85 | TBXAS1 (0.98) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10648637 | 0.84 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10844629 | 0.84 | TBXAS1 (0.70) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11030720 | 0.79 | TBXAS1 (0.70) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL19915722 | 0.79 | TBXAS1 (0.70) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11029832 | 0.76 | TBXAS1 (0.71) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11029834 | 0.76 | TBXAS1 (0.71) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11032327 | 0.75 | TBXAS1 (0.72) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11032328 | 0.75 | TBXAS1 (0.72) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11124017 | 0.75 | TBXAS1 (0.68) | TBXAS1PTGS1PTGS2PTGIS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114573-B1 | IMIDAZO(1,5-A)PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-04-20 | — | — | EP | disclosed |
| US-4588732-A | Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors | CIBA-GEIGY CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |