Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 20/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | PTGIS | Q16647 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111744 | 0.84 | TBXAS1 (0.65) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11031173 | 0.82 | TBXAS1 (0.98) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10648637 | 0.81 | TBXAS1 (1.00) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11030720 | 0.78 | TBXAS1 (0.70) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11029832 | 0.77 | TBXAS1 (0.71) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11029834 | 0.77 | TBXAS1 (0.71) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL10648281 | 0.75 | TBXAS1 (0.72) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL19915722 | 0.75 | TBXAS1 (0.70) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11200340 | 0.75 | TBXAS1 (0.80) | TBXAS1PTGS1PTGS2PTGIS | |
| SCHEMBL11032327 | 0.74 | TBXAS1 (0.72) | TBXAS1PTGS1PTGS2PTGIS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114572-A1 | Substituted imidazo(1,5-a)pyridines | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |
| EP-0068386-A1 | Substituted imidazo(1,5-a)pyridines, process for their preparation and pharmaceutical preparations containing these compounds | CIBA-GEIGY AG (CH) | 1983-01-05 | — | — | EP | disclosed |