Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.91 |
| ▸ | HPGD | P15428 | 6/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL27610516 | 1.00 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL28007731 | 0.98 | KDM4E (0.86) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL3783480 | 0.98 | KDM4E (0.86) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL503979 | 0.98 | KDM4E (0.86) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL7160601 | 0.98 | KDM4E (0.86) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6249450 | 0.97 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL31140000 | 0.95 | HPGD (0.83) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL27974441 | 0.95 | HPGD (0.83) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL10669448 | 0.95 | HPGD (0.83) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL106935 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8112 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4748910-A1 | LUBRICATING OIL COMPOSITION | Idemitsu Kosan Co.,Ltd. (JP) | 2026-05-27 | — | — | EP | claimed |
| CN-122095059-A | Contains high content of C9Lubricant composition of di-substituted diphenylamine antioxidant | — | 2026-05-26 | — | — | CN | claimed |
| CN-122060540-A | High-temperature detergency zinc-free hydraulic oil additive composition and hydraulic oil | 中国石油天然气股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| WO-2026087620-A1 | LUBRICANT COMPOSITIONS CONTAINING HIGH C9 DISUBSTITUTED DIPHENYLAMINE ANTIOXIDANT CONTENT | INFINEUM INTERNATIONAL LIMITED (GB) | 2026-04-30 | — | — | WO | claimed |
| US-20260109910-A1 | Lubricant Compositions Containing High C9 Disubstituted Diphenylamine Antioxidant Content and Low Mono- and Tri-substituted Diphenylamine Antioxidant Content | INFINEUM INTERNATTIONAL LTD (GB) | 2026-04-23 | — | — | US | claimed |
| EP-4728001-A1 | POLYAMIDE RECOVERY PROCESS | Primpex-Plastiche Riunite Italiane Import-Export- S.p.a. (IT) | 2026-04-22 | — | — | EP | claimed |
| US-12606764-B2 | Lubricating oil compositions | CHEVRON JAPAN LTD. | 2026-04-21 | — | — | US | claimed |
| US-12606766-B2 | Multipurpose oxypyridinones and their functional use-4 | INFINEUM INTERNATIONAL LIMITED (US) | 2026-04-21 | — | — | US | claimed |
| US-20260091072-A1 | FOOD PRODUCTS COMPRISING OXALIC ACID- OR OXALATE-FREE INONOTUS OBLIQUUS EXTRACT | THE BETTER FOR YOU COMPANY, LLC (US) | 2026-04-02 | — | — | US | claimed |
| US-20260078315-A1 | LUBRICATING OIL COMPOSITIONS FOR HYBRID ENGINES AND METHODS OF USE AND TESTING THEREOF | INFINEUM INTERNATIONAL LIMITED | 2026-03-19 | — | — | US | claimed |
| US-4664822-A | OVERBASED COMPOUND CONTAINING COPPER | AMOCO CORPORATION (US) | 1987-05-12 | — | — | US | claimed |
| US-4539126-A | Borated basic metal salt and lubricating oil composition | SHELL OIL COMPANY (US) | 1985-09-03 | — | — | US | claimed |
| EP-0036145-B1 | AN ORALLY ADMINISTERED DRUG FORM COMPRISING A POLAR BIOACTIVE AGENT AND AN ADJUVANT | INTERx RESEARCH CORPORATION (US) | 1985-05-29 | — | — | EP | claimed |
| US-4483854-A | Systemic treatment of psoriasis using certain salicylates | KEY PHARMACEUTICALS, INC. (US) | 1984-11-20 | — | — | US | claimed |
| EP-0089136-A2 | Oral hygiene products | THE PROCTER & GAMBLE COMPANY (US) | 1983-09-21 | — | — | EP | claimed |
| EP-0084910-A2 | High dropping-point lithium-complex grease having improved anti-noise properties | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-08-03 | — | — | EP | claimed |
| US-4171558-A | Cutting oil composition for processing cemented carbide skiving hob | IDEMITSU KOSAN CO., LTD. (JP) | 1979-10-23 | — | — | US | claimed |
| US-4141864-A | ORTHOPEDICS, DENTISTRY, IN SITU LEACHABLE PARTICLES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1979-02-27 | — | — | US | claimed |
| US-3966903-A | ALKYLENE CARBONATE | SHISEIDO CO., LTD. (JA) | 1976-06-29 | — | — | US | claimed |
| US-3964255-A | Method of inflating an automobile passenger restraint bag | SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) | 1976-06-22 | — | — | US | claimed |