Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10643880 | 0.94 | ALDH1A1 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10570063 | 0.92 | KCNH2 (0.57) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10914465 | 0.88 | ALDH1A1 (0.73) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9276997 | 0.88 | ADRB2 (0.55) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9734119 | 0.88 | ALDH1A1 (0.64) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9734115 | 0.88 | ALDH1A1 (0.64) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10527992 | 0.85 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10920186 | 0.84 | ALDH1A1 (0.58) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8703764 | 0.83 | KDM4E (0.54) | ALDH1A1ADRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL13923334 | 0.83 | ALDH1A1 (0.65) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275971-A1 | Process and intermediates for quinolonecaboxylic acid | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-07-27 | — | — | EP | disclosed |