Methacrylic Acid

Methacrylic Acid

SCHEMBL10649136

C=C(C)C(=O)O.C=CCC(O)C=CC

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
RECQL P46063 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRIK1 P39086 2/20 0.31
GRIK2 Q13002 2/20 0.31
TGFBR1 P36897 1/20 0.31
ABCC4 O15439 1/20 0.31
CYP2C19 P33261 1/20 0.30
CPA1 P15085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13560222 0.84
SCHEMBL11651521 0.84
SCHEMBL6129675 0.84
Methacrylic Acid SCHEMBL6877599 0.78 GRIK1 (0.35) MAPTGRIK1GRIK2TGFBR1ABCC4
Methacrylic Acid SCHEMBL9943230 0.78 TGFBR1 (0.38) TGFBR1
Methacrylic Acid SCHEMBL6142596 0.76 TGFBR1 (0.32) TGFBR1
Methacrylic Acid SCHEMBL29775535 0.74 TSHR (0.39) MAPTGRIK1GRIK2TGFBR1ABCC4
Methacrylic Acid SCHEMBL11132733 0.73 CYP2C19 (0.35) GRIK1GRIK2CYP2C19CPA1
Methacrylic Acid SCHEMBL3293172 0.70
Methacrylic Acid SCHEMBL18109770 0.70 ALDH1A1 (0.44) LMNATGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4725629-A Process of making an interpenetrating superabsorbent polyurethane foam KIMBERLY-CLARK CORPORATION (US) 1988-02-16 US disclosed