Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271927 | 0.87 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL11257484 | 0.84 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL29137551 | 0.83 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL5042702 | 0.82 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL11264404 | 0.81 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL2878642 | 0.80 | PTGS1 (0.55) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL2353731 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL13916496 | 0.80 | CYP2C19 (0.52) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL11338094 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL15229336 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093945-B1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-11-23 | — | — | EP | disclosed |
| US-4495192-A | HYPOTENSIVE AGENTS; VASODILATORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-01-22 | — | — | US | disclosed |
| EP-0093945-A2 | 1,4-Dihydropyridine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-11-16 | — | — | EP | disclosed |