Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257484 | 0.91 | ALDH1A1 (0.45) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11267322 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11264969 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL10649643 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11270945 | 0.81 | LMNA (0.48) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| Bicarbonate SCHEMBL11547091 | 0.80 | L3MBTL1 (0.48) | ALDH1A1LMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL13916496 | 0.80 | CYP2C19 (0.52) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11269214 | 0.80 | LMNA (0.43) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11253650 | 0.79 | CACNA1F (0.45) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11266663 | 0.79 | MAPT (0.44) | ALDH1A1LMNACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360520-A | 1,4-Dihydropyridazine compounds, and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-23 | — | — | US | disclosed |