Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 7/20 | 0.72 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679369 | 0.88 | PIN1 (0.55) | PIN1NPY5RKMT2AHPGDKDM4E | |
| SCHEMBL10938735 | 0.86 | PIN1 (0.57) | PIN1NPY5RKMT2AHPGDDHODH | |
| SCHEMBL10937913 | 0.85 | PIN1 (0.51) | PIN1NPY5RKMT2AHPGDDHODH | |
| SCHEMBL10942001 | 0.85 | PIN1 (0.51) | PIN1NPY5RKMT2AHPGDDHODH | |
| SCHEMBL10937354 | 0.85 | PIN1 (0.51) | PIN1NPY5RKMT2AHPGDKDM4E | |
| SCHEMBL316552 | 0.84 | PIN1 (1.00) | PIN1HPGDKDM4EALDH1A1PKM | |
| SCHEMBL21652629 | 0.84 | PIN1 (0.71) | PIN1NPY5RKMT2AHPGDKDM4E | |
| SCHEMBL10679043 | 0.83 | PIN1 (0.50) | PIN1NPY5RKMT2AHPGDDHODH | |
| SCHEMBL3418983 | 0.83 | NPY5R (0.50) | PIN1NPY5RKMT2AHPGDKDM4E | |
| SCHEMBL10939665 | 0.82 | NPY5R (0.49) | PIN1NPY5RKMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743586-A | PREPARATION FROM A METHYLAMINE, 2-OXIME OF ETHYL 2,3-DIOXOBUTYRATE, HYDRAZINE, TRIETHOXYMETHANE | AMERICAN CYANAMID COMPANY (US) | 1988-05-10 | — | — | US | disclosed |