Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940592 | 0.87 | NPY5R (0.47) | PIN1NPY5RKMT2AHCRTR1PKN1 | |
| SCHEMBL10649656 | 0.85 | PIN1 (0.72) | PIN1NPY5RKMT2AHCRTR1PKN1 | |
| SCHEMBL10679369 | 0.85 | PIN1 (0.55) | PIN1NPY5RKMT2AHCRTR1PKN1 | |
| SCHEMBL8964151 | 0.84 | PIN1 (0.71) | PIN1NPY5RHPGDALDH1A1KDM4E | |
| SCHEMBL10938042 | 0.83 | NPY5R (0.48) | PIN1NPY5RKMT2AHCRTR1PKN1 | |
| SCHEMBL10937354 | 0.81 | PIN1 (0.51) | PIN1NPY5RKMT2AHCRTR1PKN1 | |
| SCHEMBL10937913 | 0.81 | PIN1 (0.51) | PIN1NPY5RKMT2AHCRTR1PKN1 | |
| SCHEMBL10938735 | 0.80 | PIN1 (0.57) | PIN1NPY5RKMT2AHCRTR1HPGD | |
| SCHEMBL10679043 | 0.80 | PIN1 (0.50) | PIN1NPY5RKMT2AHCRTR1PKN1 | |
| SCHEMBL3418983 | 0.80 | NPY5R (0.50) | PIN1NPY5RKMT2AHCRTR1PKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499097-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-02-12 | — | — | US | claimed |