SCHEMBL10650108

SCHEMBL10650108

Cc1cn(C2CC(F)C(CO)C2)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.53
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
ALB P02768 1/20 0.52
POLB P06746 1/20 0.52
ADRA1A P35348 1/20 0.52
BLM P54132 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19565709 1.00 TK1 (0.53) TK1ALDH1A1LMNAALBPOLB
SCHEMBL9311032 0.92 TK1 (0.60) TK1ALDH1A1LMNAALBPOLB
SCHEMBL22382008 0.85 TK1 (0.72) TK1ALDH1A1LMNAALBPOLB
SCHEMBL13102976 0.85 TK1 (0.72) TK1ALDH1A1LMNAALBPOLB
SCHEMBL10662613 0.84 TK1 (0.53) TK1ALDH1A1LMNAALBPOLB
SCHEMBL10662619 0.84 TK1 (0.53) TK1ALDH1A1LMNAALBPOLB
SCHEMBL10666834 0.84 TK1 (0.53) TK1ALDH1A1LMNAALBPOLB
SCHEMBL9308235 0.84 TK1 (0.52) TK1ALDH1A1LMNAALBPOLB
SCHEMBL9470674 0.82 LMNA (0.55) TK1ALDH1A1LMNAALBPOLB
SCHEMBL10171803 0.82 LMNA (0.55) TK1ALDH1A1LMNAALBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277599-A2 Fluorine containing cyclopentane derivatives and processes for their production ASAHI GLASS COMPANY LTD. (JP) 1988-08-10 EP disclosed