Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ATP4A | P20648 | 2/20 | 0.47 |
| ▸ | ATP4B | P51164 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026551 | 0.84 | SMN1; SMN2 (0.54) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL10651346 | 0.84 | SMN1; SMN2 (0.54) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL11833848 | 0.83 | SMN1; SMN2 (0.52) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL16491623 | 0.80 | HTT (0.59) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL3947830 | 0.79 | SMN1; SMN2 (0.58) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL13343550 | 0.78 | L3MBTL1 (0.50) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL30858374 | 0.78 | SMN1; SMN2 (0.56) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL25679792 | 0.78 | SMN1; SMN2 (0.56) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL10645579 | 0.77 | SMN1; SMN2 (0.47) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL17544544 | 0.76 | HTT (0.55) | HTTSMN1; SMN2STAT3L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114573-B1 | IMIDAZO(1,5-A)PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-04-20 | — | — | EP | disclosed |
| US-4588732-A | Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors | CIBA-GEIGY CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| US-4470986-A | ISCHEMIA, SHOCK, THROMBOSIS | CIBA-GEIGY CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |
| EP-0114573-A1 | Imidazo(1,5-a)pyridine derivatives | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |
| EP-0114572-A1 | Substituted imidazo(1,5-a)pyridines | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |