Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | STAT3 | P40763 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATP4A | P20648 | 2/20 | 0.46 |
| ▸ | ATP4B | P51164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30858374 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT | |
| SCHEMBL16491623 | 0.83 | HTT (0.59) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT | |
| SCHEMBL17544544 | 0.82 | HTT (0.55) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT | |
| SCHEMBL3947830 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT | |
| SCHEMBL26460635 | 0.80 | MAPT (0.43) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT | |
| SCHEMBL2675108 | 0.80 | LTA4H (0.58) | SMN1; SMN2HTTL3MBTL1MAPTTDP1 | |
| SCHEMBL24992521 | 0.78 | USP28 (0.43) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT | |
| SCHEMBL2026551 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT | |
| SCHEMBL10650145 | 0.78 | HTT (0.54) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT | |
| SCHEMBL10651346 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTSTAT3L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |