Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121127 | 0.78 | HTT (0.41) | — | |
| SCHEMBL2088019 | 0.72 | CA2 (0.65) | CA2 | |
| SCHEMBL7916573 | 0.72 | CYP1A2 (0.43) | — | |
| SCHEMBL2916499 | 0.71 | CA2 (0.54) | CA2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL14317794 | 0.70 | CA2 (0.67) | CA2 | |
| SCHEMBL8113716 | 0.69 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL8120260 | 0.69 | CYP1A2 (0.41) | — | |
| SCHEMBL4236683 | 0.69 | CA2 (0.67) | CA2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL25646052 | 0.68 | CYP1A2 (0.39) | — | |
| SCHEMBL792780 | 0.66 | CA2 (1.00) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271273-A2 | Thieno-and furopyridine sulfonamides | MERCK & CO. INC. (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4731368-A | Thienopyridine sulfonamides and their ophthalmological formulation | MERCK & CO., INC. (US) | 1988-03-15 | — | — | US | disclosed |