Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.40 |
| ▸ | AHR | P35869 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 2/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655134 | 0.84 | KDM4E (0.43) | PRKCZADORA2AADORA1MAPTALOX15 | |
| SCHEMBL10653878 | 0.82 | ADORA1 (0.43) | PRKCZADORA2AADORA1MAPTHTT | |
| SCHEMBL10656806 | 0.79 | NPSR1 (0.42) | PRKCZADORA2AADORA1MAPTHTT | |
| SCHEMBL20636491 | 0.78 | MAPK14 (0.43) | MAPK14PRKCZAHRADORA2AADORA1 | |
| SCHEMBL10651575 | 0.78 | PDCD1 (0.46) | PRKCZADORA2AADORA1MAPTALDH1A1 | |
| SCHEMBL10655060 | 0.77 | GRIA4 (0.47) | ADORA2AADORA1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL10656075 | 0.77 | HPGD (0.46) | MAPTHSD17B10NPC1ALDH1A1RAB9A | |
| SCHEMBL10654269 | 0.77 | ALDH1A1 (0.47) | ADORA2AADORA1MAPTALOX15HSD17B10 | |
| SCHEMBL10655150 | 0.76 | MAPK14 (0.40) | MAPK14PRKCZAHRADORA2AADORA1 | |
| SCHEMBL10656103 | 0.75 | ALDH1A1 (0.52) | PRKCZADORA2AADORA1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |