Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 4/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656806 | 0.83 | NPSR1 (0.42) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL10651575 | 0.82 | PDCD1 (0.46) | ALDH1A1MAPTKDM4ENPSR1RXFP1 | |
| SCHEMBL10655134 | 0.82 | KDM4E (0.43) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL10655060 | 0.81 | GRIA4 (0.47) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL13991789 | 0.80 | PRKCZ (0.47) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL10654580 | 0.79 | CYP2A6 (0.40) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL15629589 | 0.79 | PRKCZ (0.68) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL10653315 | 0.78 | KIF11 (0.42) | ALDH1A1MAPTKDM4ERXFP1PTPN1 | |
| SCHEMBL10656293 | 0.75 | PRKCZ (0.43) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL10651211 | 0.75 | MAPK14 (0.40) | ALDH1A1MAPTPRKCZADORA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |