Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913673 | 0.81 | HTR2A (0.39) | TRPV1HTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL15075066 | 0.81 | TRPV1 (0.39) | TRPV1KDM1ARCOR1 | |
| SCHEMBL20616572 | 0.81 | TRPV1 (0.39) | TRPV1KDM1ARCOR1 | |
| SCHEMBL10653035 | 0.78 | KCNE1 (0.36) | HTR2AKDM1AHTR2CHTR2BKMT2A | |
| SCHEMBL23422976 | 0.75 | KMT2A (0.57) | TRPV1KMT2A | |
| SCHEMBL10851336 | 0.74 | MAPK1 (0.41) | TRPV1HTR2BKMT2A | |
| SCHEMBL10851346 | 0.74 | HTR2A (0.44) | TRPV1HTR2A | |
| SCHEMBL10653261 | 0.74 | TRPV1 (0.40) | TRPV1KMT2A | |
| SCHEMBL11096388 | 0.73 | MAPK1 (0.36) | TRPV1 | |
| SCHEMBL10850317 | 0.73 | MAPK1 (0.36) | TRPV1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157267-B1 | SUBSTITUTED BENZOPYRANS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0114374-B1 | SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0157267-A2 | Substituted benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0114374-A1 | Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines | BAYER AG (DE) | 1984-08-01 | — | — | EP | disclosed |