Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.64 |
| ▸ | RELA | Q04206 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.57 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062661 | 0.87 | ALDH1A1 (0.64) | ALDH1A1HPGDSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL3323394 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HPGDSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL798337 | 0.87 | ALDH1A1 (0.73) | ALDH1A1HPGDSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL15167569 | 0.87 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL19103511 | 0.86 | HTT (0.61) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13887595 | 0.86 | NR4A3 (0.72) | ALDH1A1HPGDSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL3057553 | 0.86 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2RAB9AHTT | |
| SCHEMBL3264275 | 0.86 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL5069717 | 0.86 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL1143334 | 0.86 | ALDH1A1 (1.00) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025105857-A1 | HETEROARYL-DERIVATIVE COMPOUND AND USE THEREOF | (주)신테카바이오 | 2025-05-22 | — | — | WO | disclosed |
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | disclosed |
| EP-3087058-B1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF PYRAZOLES | ISAGRO SPA (IT) | 2017-09-06 | — | — | EP | disclosed |
| US-9676726-B2 | Process for the regioselective synthesis of pyrazoles | ISAGRO S.P.A. (IT) | 2017-06-13 | — | — | US | disclosed |
| US-9676726-B2 | Process for the regioselective synthesis of pyrazoles | ISAGRO S.P.A. (IT) | 2017-06-13 | — | — | US | disclosed |
| US-20160318874-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF PYRAZOLES | FMC IP TECHNOLOGY GMBH (CH) | 2016-11-03 | — | — | US | disclosed |
| US-20160318874-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF PYRAZOLES | FMC IP TECHNOLOGY GMBH (CH) | 2016-11-03 | — | — | US | disclosed |
| US-20160295864-A1 | ETHEREAL OXYGEN ATOM-CONTAINING PERFLUOROALKYL GROUP-SUBSTITUTED PYRAZOLE RING COMPOUND AND METHOD FOR ITS PRODUCTION | ASAHI GLASS COMPANY, LIMITED (JP) | 2016-10-13 | — | — | US | disclosed |
| EP-2308838-B1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLYL COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-9150563-B2 | Nitrogen-containing aromatic heterocyclyl compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-10-06 | — | — | US | disclosed |
| EP-1594438-A2 | USE OF AN INHIBITOR OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE IN ORDER TO STIMULATE PIGMENTATION OF THE SKIN OR SKIN APPENDAGES | L'OREAL (FR) | 2005-11-16 | — | — | EP | disclosed |
| US-20050239797-A1 | Isoquinoline and quinazoline derivatives having a combined 5HT1A, 5HT1B, and 5HT1D receptor activity | SMITHKLINE BEECHAM, PLC | 2005-10-27 | — | — | US | disclosed |
| EP-1565150-A1 | COMPOSITION FOR HAIR CARE OR EYELASHES CONTAINING A PYRAZOL-CARBOXAMIDE, ITS USE FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR PREVENTING LOSS THEREOF | L'OREAL (FR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |
| EP-1228043-B1 | ISOQUINOLINE AND QUINAZOLINE DEIVATIVES HAVING A COMBINED 5HT1A, 5HT1B AND 5HT1D RECEPTOR ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-20040235831-A1 | Composition for caring for the hair or the eyelashes, containing a pyrazolecarboxamide compound, use thereof for stimulating the growth of the hair and the eyelashes and/or for reducing their loss | SOCIETE L'OREAL, S.A. (FR) | 2004-11-25 | — | — | US | disclosed |
| WO-2004073594-A2 | USE OF AN INHIBITOR OF 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE IN ORDER TO STIMULATE PIGMENTATION OF THE SKIN OR SKIN APPENDAGES | L'OREAL (FR) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004047776-A1 | COMPOSITION FOR HAIR CARE OR EYELASHES CONTAINING A PYRAZOL-CARBOXAMIDE, ITS USE FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR PREVENTING LOSS THEREOF | L'OREAL (FR) | 2004-06-10 | — | — | WO | disclosed |
| EP-1228043-A1 | ISOQUINOLINE AND QUINAZOLINE DEIVATIVES HAVING A COMBINED 5HT1A, 5HT1B AND 5HT1D RECEPTOR ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001032626-A1 | ISOQUINOLINE AND QUINAZOLINE DERIVATIVES HAVING A COMBINED 5HT1A, 5HT1B AND 5HT1D RECEPTOR ACTIVITY | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318874-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF PYRAZOLES | CYP4F11, CYP2F1, CYP3A4 | ALDH1A1 273/4885HPGD 169/4885SMN1; SMN2 4801/4885 |
| US-20160295864-A1 | ETHEREAL OXYGEN ATOM-CONTAINING PERFLUOROALKYL GROUP-SUBSTITUTED PYRAZOLE RING COMPOUND AND METHOD FOR ITS PRODUCTION | CYP2F1, CYP2E1, CYP2C19 | ALDH1A1 738/4885HPGD 1194/4885SMN1; SMN2 4279/4885 |
| US-20050239797-A1 | Isoquinoline and quinazoline derivatives having a combined 5HT1A, 5HT1B, and 5HT1D receptor activity | HTR1B, HTR1A, HTR1D | ALDH1A1 489/4885HPGD 1763/4885SMN1; SMN2 1271/4885 |
| US-20040235831-A1 | Composition for caring for the hair or the eyelashes, containing a pyrazolecarboxamide compound, use thereof for stimulating the growth of the hair and the eyelashes and/or for reducing their loss | BCOR, HCRTR1, RCOR1 | ALDH1A1 3475/4885HPGD 3731/4885SMN1; SMN2 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.