Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986922 | 0.86 | KDM4E (0.47) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 | |
| SCHEMBL27170735 | 0.85 | KDM4E (0.45) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 | |
| SCHEMBL10907310 | 0.84 | KDM4E (0.46) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 | |
| SCHEMBL6671333 | 0.83 | ALDH1A1 (0.47) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 | |
| SCHEMBL10908205 | 0.83 | KDM4E (0.46) | KDM4EMAPK1NPSR1MAPTLMNA | |
| SCHEMBL9638081 | 0.81 | MEN1 (0.43) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 | |
| SCHEMBL1535625 | 0.81 | MAPK1 (0.48) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 | |
| SCHEMBL958236 | 0.80 | EGFR (0.48) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 | |
| SCHEMBL29607317 | 0.80 | EGFR (0.48) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 | |
| SCHEMBL986849 | 0.80 | KDM4E (0.49) | KDM4EMAPK1NPSR1CYP2C19PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111448-B1 | COLOUR-PHOTOGRAPHIC RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |
| US-4629682-A | STERICALLY HINDERED PHENOL-CONTAINING PHOTOSTABILIZERS; | CIBA-GEIGY AG (CA) | 1986-12-16 | — | — | US | disclosed |
| EP-0111448-A2 | Colour-photographic recording material | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | disclosed |
| US-4452884-A | 2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HYDROXYPHENYL ALKYL AMIDES OR ESTERS AS LIGHT STABILIZERS | CIBA-GEIGY AG (CH) | 1984-06-05 | — | — | US | disclosed |