Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607317 | 1.00 | EGFR (0.48) | EGFRMAPK1LMNAHTTKDM4E | |
| SCHEMBL27170735 | 0.91 | KDM4E (0.45) | EGFRMAPK1LMNAHTTKDM4E | |
| SCHEMBL1535626 | 0.84 | LMNA (0.51) | MAPK1LMNAHTTKDM4ENPSR1 | |
| SCHEMBL6902107 | 0.83 | ALDH1A1 (0.40) | EGFRMAPK1LMNAHTTKDM4E | |
| SCHEMBL1042008 | 0.82 | USP2 (0.44) | EGFRMAPK1LMNAHTTKDM4E | |
| SCHEMBL30087029 | 0.82 | USP2 (0.44) | EGFRMAPK1LMNAHTTKDM4E | |
| SCHEMBL6671333 | 0.81 | ALDH1A1 (0.47) | MAPK1HTTKDM4ENPSR1CYP2C19 | |
| SCHEMBL23120088 | 0.81 | RBP4 (0.45) | MAPK1LMNAHTTPTGDR2SMN1; SMN2 | |
| SCHEMBL12772150 | 0.81 | ALDH1A1 (0.50) | EGFRMAPK1LMNAHTTKDM4E | |
| SCHEMBL29607406 | 0.81 | RBP4 (0.45) | MAPK1LMNAHTTPTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12291593-B2 | Compounds for use in catalyst compositions for the production of polyolefins | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2025-05-06 | — | — | US | disclosed |
| EP-4031592-B1 | COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-04-30 | — | — | EP | disclosed |
| CN-114423769-B | Compounds in catalyst compositions for the production of polyolefins | SABIC环球技术有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| US-20220356275-A1 | COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2022-11-10 | — | — | US | disclosed |
| CN-114423769-A | Compounds for use in catalyst compositions for the production of polyolefins | SABIC环球技术有限责任公司 | 2022-04-29 | — | — | CN | disclosed |
| EP-2456795-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2456793-A1 | CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158733-B2 | Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands | EQUISTAR CHEMICALS, LP (US) | 2012-04-17 | — | — | US | disclosed |
| WO-2011011039-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011011039-A1 | METHOD OF PREPARING NON-METALLOCENE CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| US-20110021344-A1 | Method for preparing non-metallocene ligands | EQUISTAR CHEMICALS, LP | 2011-01-27 | — | — | US | disclosed |
| EP-2272852-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | Sumitomo Chemical Company, Limited (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-20090143620-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED | 2009-06-04 | — | — | US | disclosed |
| US-7482414-B2 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-27 | — | — | US | disclosed |
| US-7482414-B2 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20070135600-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | US | disclosed |
| US-20070135600-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356275-A1 | COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS | RPLP0, RPS20, RPS10 | EGFR 601/4885MAPK1 2744/4885LMNA 1510/4885 |
| US-20070135600-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | AP1M1, OR10J3, AP2M1 | EGFR 895/4885MAPK1 1478/4885LMNA 3039/4885 |
| US-20090143620-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | AP1M1, OR10J3, AP2M1 | EGFR 895/4885MAPK1 1478/4885LMNA 3039/4885 |
| US-12291593-B2 | Compounds for use in catalyst compositions for the production of polyolefins | RPLP0, RPS20, RPS10 | EGFR 601/4885MAPK1 2744/4885LMNA 1510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.