Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 15/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651251 | 1.00 | HPGD (0.68) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25855470 | 0.85 | HPGD (0.73) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3536564 | 0.82 | MAPT (0.97) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22094933 | 0.82 | MAPT (0.97) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL40059 | 0.81 | HPGD (0.68) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL21066338 | 0.81 | MAPT (0.73) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8074050 | 0.81 | LMNA (0.97) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL30416098 | 0.81 | HPGD (0.68) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3837554 | 0.81 | HPGD (1.00) | HPGDMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12478410 | 0.81 | MAPT (0.73) | HPGDMAPTALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252503-A1 | Aminoimidazoquinoline derivatives | Bristol-Myers Squibb Company (US) | 1988-01-13 | — | — | EP | disclosed |