Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.97 |
| ▸ | MAPT | P10636 | 15/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381562 | 1.00 | LMNA (0.97) | LMNAMAPTRECQLSIRT6HPGD | |
| SCHEMBL3109069 | 0.98 | LMNA (1.00) | LMNAMAPTRECQLSIRT6HPGD | |
| SCHEMBL30059159 | 0.98 | LMNA (1.00) | LMNAMAPTRECQLSIRT6HPGD | |
| SCHEMBL25877527 | 0.95 | LMNA (0.94) | LMNAMAPTRECQLSIRT6HPGD | |
| SCHEMBL18393128 | 0.86 | LMNA (0.72) | LMNAMAPTRECQLSIRT6HPGD | |
| SCHEMBL14892360 | 0.86 | SIRT6 (0.89) | LMNAMAPTRECQLSIRT6HPGD | |
| SCHEMBL979867 | 0.85 | LMNA (0.77) | LMNAMAPTRECQLSIRT6HPGD | |
| SCHEMBL25855470 | 0.85 | HPGD (0.73) | LMNAMAPTHPGDALDH1A1CYP1A2 | |
| SCHEMBL25369256 | 0.84 | LMNA (0.70) | LMNAMAPTRECQLSIRT6HPGD | |
| SCHEMBL77148 | 0.84 | SIRT6 (1.00) | LMNAMAPTRECQLSIRT6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |