Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.43 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14131214 | 0.88 | SLC7A5 (0.57) | SLC7A5HDAC8HDAC6SCN9ADHODH | |
| SCHEMBL16620907 | 0.83 | ANPEP (0.55) | MRGPRX4SMN1; SMN2 | |
| SCHEMBL10279297 | 0.82 | TAS1R3 (0.61) | HPGDSMN1; SMN2 | |
| SCHEMBL10563978 | 0.81 | PLK1 (0.62) | SLC7A5HDAC8HDAC6HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL10565549 | 0.80 | PLK1 (0.60) | SLC7A5HDAC8HDAC6HPGDKMT2A | |
| SCHEMBL3414665 | 0.80 | CYP4F2 (0.66) | SLC7A5HDAC8HDAC6DHODHMRGPRX4 | |
| SCHEMBL5254691 | 0.80 | SLC7A5 (0.57) | SLC7A5HDAC8HDAC6DHODHMRGPRX4 | |
| SCHEMBL13844842 | 0.80 | PLK1 (0.64) | SLC7A5HDAC8HDAC6DHODHMRGPRX4 | |
| SCHEMBL10160020 | 0.78 | SLC7A5 (0.68) | SLC7A5HDAC8HDAC6HPGDMRGPRX4 | |
| SCHEMBL6388386 | 0.78 | LOXL2 (0.65) | SLC7A5HDAC8HDAC6DHODHMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157267-B1 | SUBSTITUTED BENZOPYRANS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4659737-A | Substituted aminomethyl benzopyrans having anti-hypertensive activities | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| US-4647579-A | Circulation active novel substituted 4-hydroxy-benzopyrans | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-03 | — | — | US | disclosed |
| EP-0157267-A2 | Substituted benzopyrans, process for their preparation and their use in medicines | BAYER AG (DE) | 1985-10-09 | — | — | EP | disclosed |