SCHEMBL10651309

SCHEMBL10651309

CC(N1C(=O)c2c(Br)c(Br)c3c(Br)c(Br)ccc3c2C1=O)N1C(=O)c2c(Br)c(Br)c3c(Br)c(Br)ccc3c2C1=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 1/20 0.31
USP2 O75604 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352144 0.78 CA12 (0.42) CA9
SCHEMBL2769359 0.75 TSHR (0.35) CA9
SCHEMBL9272983 0.68 TSHR (0.50)
SCHEMBL10935467 0.63 USP2 (0.37) CA9USP2
SCHEMBL3498822 0.62 KDM4E (0.38)
SCHEMBL14000458 0.59 ALDH1A1 (0.43)
SCHEMBL9812564 0.58 KDM4E (0.34)
SCHEMBL9331108 0.57 TSHR (0.36) CA9
SCHEMBL20356138 0.56 KDM4E (0.34)
SCHEMBL5096156 0.56 CA12 (0.35) CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0117691-B1 FLEXIBLE POLYURETHANE FOAMS WITH FLAME AND EMBER DRIP RETARDANCE STAUFFER CHEMICAL COMPANY (US) 1988-10-05 EP claimed