SCHEMBL9352144

SCHEMBL9352144

O=C1c2c(Br)c(Br)c3c(Br)c(Br)ccc3c2C(=O)N1CCN1C(=O)c2c(Br)c(Br)c3c(Br)c(Br)ccc3c2C1=O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA7 P43166 3/20 0.42
CA9 Q16790 3/20 0.42
CA4 P22748 1/20 0.42
CYP1B1 Q16678 11/20 0.35
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
PABPC1 P11940 1/20 0.33
KMT2A Q03164 1/20 0.33
TERT O14746 3/20 0.33
CASP3 P42574 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10651309 0.78 CA9 (0.31) CA9
SCHEMBL94242 0.73 CA9 (0.49) CA12CA1CA2CA7CA9
SCHEMBL29366486 0.73 CA9 (0.49) CA12CA1CA2CA7CA9
SCHEMBL9769322 0.72 RAB9A (0.42) CA12CA1CA2CA7CA9
SCHEMBL9272983 0.70 TSHR (0.50) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL11295187 0.65 CA1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL5090368 0.65 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL3498822 0.65 KDM4E (0.38) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL10570526 0.64 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL6570337 0.64 CA12 (0.45) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348222-B1 Process for preparing flame retardant bisimide product ALBEMARLE CORP (US) 1994-09-21 EP disclosed
US-5136047-A Process for preparing flame retardant bisimide product ETHYL CORPORATION (US) 1992-08-04 US disclosed
US-4914212-A REACTING TETRABROMOPHTHALIC ANHYDRIDE WITH A DIAMINE OR ITS SALT IN ANHYDROUS SOLUTION CONTAINING CARBOXYLIC ACID ETHYL CORPORATION (US) 1990-04-03 US disclosed
EP-0348222-A1 Process for preparing flame retardant bisimide product ALBEMARLE CORPORATION (US) 1989-12-27 EP disclosed