Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29574966 | 0.89 | MAPT (0.59) | PTPRACYP1A2CYP3A4KCNA5SMN1; SMN2 | |
| SCHEMBL6424354 | 0.84 | PTPRA (0.50) | PTPRACYP1A2KCNA5SMN1; SMN2MAPT | |
| SCHEMBL4621398 | 0.84 | PTPRA (0.50) | PTPRACYP1A2KCNA5SMN1; SMN2MAPT | |
| SCHEMBL4621412 | 0.84 | PTPRA (0.50) | PTPRACYP1A2KCNA5SMN1; SMN2MAPT | |
| SCHEMBL6573455 | 0.84 | PTPRA (0.50) | PTPRACYP1A2CYP3A4KCNA5SMN1; SMN2 | |
| SCHEMBL13936656 | 0.81 | KMT2A (0.51) | PTPRACYP1A2KCNA5SMN1; SMN2MAPT | |
| SCHEMBL1066703 | 0.81 | PTPRA (0.50) | PTPRACYP1A2KCNA5SMN1; SMN2MAPT | |
| SCHEMBL8167442 | 0.80 | MAPT (0.53) | PTPRACYP1A2CYP3A4KCNA5SMN1; SMN2 | |
| SCHEMBL7095634 | 0.79 | TDP1 (0.57) | CYP1A2KCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL10261336 | 0.79 | MAPT (0.57) | CYP1A2KCNA5SMN1; SMN2MAPTLIN28A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9913917-B2 | Biocompatible fluorescent metal oxide nanoparticles | VISEN MEDICAL, INC. (US) | 2018-03-13 | — | — | US | disclosed |
| EP-2963017-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-1482985-B1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-20110229410-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2011-09-22 | — | — | US | disclosed |
| US-7875258-B2 | For use as radiopharmaceuticals; solid phase synthesis; conjugation with DNA and G-protein-coupled receptors; high binding affinity, high labeling yield, superior retention and versatility; labeling without the need for co-ligands; simplification | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2011-01-25 | — | — | US | disclosed |
| US-20100303725-A1 | Technetium- and Rhenium-Bis(heteroaryl) Complexes, and Methods of Use Thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-12-02 | — | — | US | disclosed |
| US-7824661-B2 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| EP-1713515-A4 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2009-07-22 | — | — | EP | disclosed |
| US-20090023787-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-01-22 | — | — | US | disclosed |
| US-7381399-B2 | Technetium-dipyridine complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-20080025915-A1 | Technetium-And Rhenium-Bis (Heteroaryl) Complexes, And Methods Of Use Thereof | CITIZENS BANK, N.A. | 2008-01-31 | — | — | US | disclosed |
| EP-1713515-A1 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2006-10-25 | — | — | EP | disclosed |
| EP-1482985-A4 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2006-06-28 | — | — | EP | disclosed |
| US-20060034758-A1 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2006-02-16 | — | — | US | disclosed |
| WO-2005079865-A1 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2005-09-01 | — | — | WO | disclosed |
| EP-1482985-A2 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | Biostream, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20030235843-A1 | Technetium-depyridine complexes, and methods of use thereof | CITIZENS BANK, N.A. | 2003-12-25 | — | — | US | disclosed |
| WO-2003077727-A2 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | BIOSTREAM, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229410-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | SLC7A5, SLC7A1, AADAT | PTPRA 3361/4885CYP1A2 4474/4885CYP3A4 3500/4885 |
| US-20030235843-A1 | Technetium-depyridine complexes, and methods of use thereof | SLC7A5, DNPEP, SLC7A1 | PTPRA 3642/4885CYP1A2 4580/4885CYP3A4 3847/4885 |
| US-20100303725-A1 | Technetium- and Rhenium-Bis(heteroaryl) Complexes, and Methods of Use Thereof | SLC7A5, RAB35, AADAT | PTPRA 4321/4885CYP1A2 4605/4885CYP3A4 4271/4885 |
| US-20060034758-A1 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | SLC7A5, RAB35, AADAT | PTPRA 4321/4885CYP1A2 4605/4885CYP3A4 4271/4885 |
| US-20090023787-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | SLC7A5, SLC7A1, AADAT | PTPRA 3361/4885CYP1A2 4474/4885CYP3A4 3500/4885 |
| US-20080025915-A1 | Technetium-And Rhenium-Bis (Heteroaryl) Complexes, And Methods Of Use Thereof | SLC7A5, RAB35, AADAT | PTPRA 4321/4885CYP1A2 4605/4885CYP3A4 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.