Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497469 | 0.87 | FNTA (0.46) | PTPRAFNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL1065198 | 0.84 | PTPRA (0.53) | PTPRAFNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL32662174 | 0.83 | CYP1A2 (0.46) | PTPRAFNTAFNTBCYP1A2KCNA5 | |
| SCHEMBL19349131 | 0.79 | MEN1 (0.61) | L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL14004817 | 0.78 | FNTA (0.53) | PTPRAFNTAFNTBCYP1A2KCNA5 | |
| SCHEMBL29574966 | 0.77 | MAPT (0.59) | PTPRAFNTAFNTBCYP1A2CYP3A4 | |
| SCHEMBL4621398 | 0.76 | PTPRA (0.50) | PTPRAFNTAFNTBCYP1A2KCNA5 | |
| SCHEMBL6424354 | 0.76 | PTPRA (0.50) | PTPRAFNTAFNTBCYP1A2KCNA5 | |
| SCHEMBL4621412 | 0.76 | PTPRA (0.50) | PTPRAFNTAFNTBCYP1A2KCNA5 | |
| SCHEMBL6204342 | 0.76 | KDM4E (0.52) | PTPRACYP1A2CYP3A4KCNA5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131042-B1 | COLORANTS WITH TRANSITION METAL COMPLEXES | HENKEL KGAA (DE) | 2004-01-21 | — | — | EP | disclosed |
| EP-1131042-A2 | COLORANTS WITH TRANSITION METAL COMPLEXES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029036-A2 | COLORANTS WITH TRANSITION METAL COMPLEXES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-05-25 | — | — | WO | disclosed |