Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130389 | 0.76 | IMPDH2 (0.39) | IMPDH2NUAK1IGF1RMETPIM1 | |
| SCHEMBL30804568 | 0.72 | GRIN2D (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1609100 | 0.71 | IMPDH1 (0.45) | IMPDH2NUAK1IGF1RMETPIM1 | |
| SCHEMBL1502252 | 0.68 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1608266 | 0.67 | NUAK1 (0.43) | IMPDH2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28045740 | 0.65 | GRIN2D (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL27609737 | 0.62 | ALDH1A1 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29242781 | 0.61 | MAPT (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9694476 | 0.60 | GRIN2D (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3476285 | 0.59 | MAPT (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60226811-A | — | — | None | — | — | JP | disclosed |
| JP-61151184-A | — | — | None | — | — | JP | disclosed |
| EP-0161499-B1 | PROCESS FOR PREPARATION OF AMINOPHTHALIDEISOQUINOLINES | MITSUBISHI KASEI CORPORATION (JP) | 1988-07-27 | — | — | EP | disclosed |
| US-4684732-A | Process for preparation of phthalide derivatives | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0201359-A2 | Use of phthalide isoquinoline derivatives for treatments inhibiting the formation of lipid peroxides | MITSUBISHI KASEI CORPORATION (JP) | 1986-11-12 | — | — | EP | disclosed |
| JP-S61151184-A | PRODUCTION OF NITROPHTHALIDE | MITSUBISHI CHEM IND LTD | 1986-07-09 | — | — | JP | disclosed |
| EP-0161499-A1 | Process for preparation of aminophthalideisoquinolines | MITSUBISHI KASEI CORPORATION (JP) | 1985-11-21 | — | — | EP | disclosed |
| JP-S60226811-A | ANTIARTERIOSCLEROTIC | MITSUBISHI CHEM IND LTD | 1985-11-12 | — | — | JP | disclosed |
| US-4302458-A | ANTIALLERGENS | LABOREC LABORATOIRE DE RECHERCHES BIOLOGIQUES (FR) | 1981-11-24 | — | — | US | disclosed |